We prove it with data.

Our findings are published in peer-reviewed journals like the American Journal of Therapeutics and Journal of Pharmacy Research, vetted by experts to confirm the rigor and impact of our trials. Theramine’s success isn’t just a claim—it’s a fact backed by science.

We target pain at its roots.

We harness a precise blend of amino acid precursors, think arginine, tryptophan, and serine, to tackle the neurotransmitter deficiencies driving chronic pain. Our approach doesn’t mask symptoms; it’s measured in reduced inflammation, improved function, and relief you can feel.

We keep pushing the boundaries.

With three major clinical studies already completed—and more in the works—we’re relentless about refining Theramine. Our ongoing research ensures we stay ahead of the curve, delivering cutting-edge pain relief that evolves with the latest discoveries.

Theramine is clinically proven to reduce pain and enhance function.

63%
of patients experienced a significant reduction in chronic back pain after 28 days with Theramine and ibuprofen combined.
62%
of patients saw improved daily function and less disability after 28 days with Theramine and ibuprofen combined.
⭐ ⭐ ⭐ ⭐ ⭐
James R., 67, Retired Carpenter
- Verified Customer
⭐ ⭐ ⭐ ⭐ ⭐
Sarah M., 52, Office Manager
- Verified Customer
⭐ ⭐ ⭐ ⭐ ⭐
Emily T., 38, Yoga Instructor
- Verified Customer
⭐ ⭐ ⭐ ⭐ ⭐
Robert K., 71, Grandfather
- Verified Customer
⭐ ⭐ ⭐ ⭐ ⭐
Lisa P., 45, Nurse
- Verified Customer

Benefits you can feel.

Formula benefits

Noticeably reduced back pain¹

Less daily stiffness and discomfort¹

Improved mobility and function that lasts¹

Shell WE et al. Am J Ther. 2014. / Shell WE et al. Am J Ther. 2012.

Patients also reported

Lower reliance on breakthrough pain meds

Enhanced ease in daily activities without side effects

Shell WE et al. Am J Ther. 2014. / Shell WE et al. Am J Ther. 2012.

Research that’s vetted by the scientific community.

Our pain relief research has been featured in multiple scientific outlets, including 3 peer-reviewed medical journal publications.

American Journal of Therapeutics

Reduction in Pain and Inflammation Associated With Chronic Low Back Pain With the Use of the Medical Food Theramine.
Read The Study

Journal of Pharmacy Research

Theramine (A Medical Food) Versus Non-Steroidal Anti-Inflammatory Agents in Elderly Patients: A Pharmacoeconomic Analysis.
Read The Study

American Journal of Therapeutics

A Double-Blind Controlled Trial of a Single Dose Naproxen and an Amino Acid Medical Food Theramine for the Treatment of Low Back Pain.
Read The Study

Trusted by Physicians.

Dr. David Silver
Board certified in internal medicine and rheumatology. Former Clinical Chief of Rheumatology at Cedars Sinai Medical Center.
Dr. Schneider
Dr. May

We’re serious about facts. Ask away.

A clinical study is a research project that tests how a product—like Theramine—affects people. For Theramine, studies measure its ability to reduce chronic back pain and inflammation in real patients, using tools like pain scales and blood tests. It’s all about gathering solid evidence to show what works and why.

Theramine’s studies are carefully planned to compare it against common pain relievers like ibuprofen or naproxen, or a combination of both. They use large groups and track specific outcomes—like pain reduction and mobility—over 28 days. This design proves Theramine’s effectiveness and safety in a real-world setting, giving doctors and patients trustworthy results.

A publication is a detailed report of a study shared in a scientific journal, like American Journal of Therapeutics. Peer-review means experts in the field check the research for accuracy and quality before it’s published. For Theramine, this stamp of approval ensures our findings—like cutting pain by over 60%—are credible and not just marketing hype.

“Statistically significant” means the results aren’t due to chance—they’re real and reliable. In Theramine’s studies, when pain dropped by 50.3% with Theramine alone versus barely changing with ibuprofen (P<0.05), it showed a clear, meaningful difference. It’s a way to trust that Theramine actually works.

A randomized, placebo-controlled trial splits participants randomly into groups—some get Theramine, others get a placebo (a dummy pill) or a drug like ibuprofen. This setup, used in Theramine’s research, ensures the results come from the treatment itself, not expectations or bias, proving its true impact on pain and inflammation.

“Double-blind” means neither the patients nor the researchers know who’s getting Theramine, ibuprofen, or a placebo until the study ends. Theramine’s double-blind trials (e.g., 2014 and 2012 studies) prevent bias, so the 63% pain reduction we saw is a genuine outcome, not influenced by anyone’s hopes or guesses.

No, the FDA doesn’t require clinical studies for medical foods, which Theramine is classified as, since they’re regulated differently from drugs or supplements—no pre-approval is needed. But we conducted them anyway (e.g., published in 2014 and 2012) to show Theramine’s safety and effectiveness with hard data, going beyond what’s required for your peace of mind.